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Locate Available Clinical Trials

To view available Clinical Trial information choose from the list on the right or search using the fields below.

 

 

trial #
trial description
  • Alliance A221101
  • The purpose of this study is to see if taking the study drug, armodafinil, at a dose of 150mg or 250mg, will improve problems with fatigue in patients who have been diagnosed with brain cancer and are experiencing fatigue. In this study, you will take either the study drug, armodafinil, or the placebo (inactive drug).  You will not take both. 

  • NRG GY008
  • NRG-CC004
  • Sexual health after treatment for cancer is an important survivorship issue. This study will address the common side effect of decreased sexual health in women who have been treated for breast or gynecologic cancer. The study will test whether bupropion, a medication that is approved for depression and smoking cessation can improve sexual desire compared to placebo. 

  • NRG-GY004
  • The purpose of this study is to compare the effect on your ovarian, peritoneal or fallopian tube cancer of using either olaparib by itself or the combination of cediranib and olaparib to the usual chemotherapy given for your cancer (carboplatin and paclitaxel; carboplatin and gemcitabine; or carboplatin and pegylated liposomal doxorubicin [PLD]). Any of these different approaches could shrink your cancer but could also cause side effects. This study will allow the researchers to learn whether giving olaparib by itself or giving the combination of cediranib and olaparib is better, the same, or worse than the usual chemotherapy by observing both the effect of these treatments on your cancer as well as any side effects that may be experienced. 

  • NRG-GY005
  • The purpose of the Phase II part of the study is to compare any good and bad effects of using a combination of the investigational agents cediranib and olaparib, to using the standard chemotherapy, or cediranib alone, or olaparib alone. Cediranib is an experimental drug that may help keep the fallopian tube or primary peritoneal cancer cells from growing by affecting their blood supply. Olaparib is a drug that may stop cancer cells from growing abnormally. 

     

  • NRG-GY006
  • The purpose of this study is to compare any good or bad effects of adding triapine to the usual cisplatin chemotherapy and radiation therapy, compared to using cisplatin chemotherapy and radiation therapy alone for your vaginal or uterine cancer.  The addition of triapine to the usual chemotherapy and radiation therapy could shrink your tumor and increase the length of time untill the cancer returns, but it could also cause side effects. This study will allow the researchers to know whether this different approach is better, the same, or worse than the usual approach. 

  • NRG/GOG 0225
  • The purpose of this study is to find out if a change in diet and exercise in women with primary peritoneal, fallopian tube and ovarian cancer has an effect on the length of time you are cancer free following your initial treatment.

  • NRG/GOG 0237
  • The main purpose of this study is to determine whether the presence of human Papillomavirus (called HPV) and certain chemical substances (called biomarkers) in cervical cells can help identify which women with a cytologic diagnosis of AGC have a benign condition and which have a pre-cancerous condition or an invasive cancer that requires surgical removal.  

  • NRG/GOG 0238
  • The purpose of this study is to compare radiation therapy in combination with weekly treatment with the chemotherapy drug cisplatin to the standard treatment for uterine cancer. The standard treatment for this type of cancer is radiation therapy alone.

  • NRG/GOG 0263
  • Cervical cancer is classified as low, intermediate, and high risk based on the pathology findings. Women with early cervical cancer with the most concerning pathology findings for recurrence of cancer or "high risk" are treated with radiation and chemotherapy. Women with "intermediate risk" are treated with radiation alone. The purpose of this study is to determine if weekly chemotherapy with cisplatin along with radiation therapy increases disease-free time compared to radiation therapy alone.

  • NRG/GOG 0264
  • The purpose of this study is to find out whether treatment with the drugs paclitaxel and carboplatin work better to control ovarian cancer than treatment with the drugs bleomycin, etoposide, and cisplatin, which is the standard treatment for your type of cancer. Another purpose of this study is to find out what side effects are caused by treatment with these drug combinations.

  • NRG/GOG 286B
  • The purpose of this study is to find out if the drug combination of paclitaxel, carboplatin and metformin works better than paclitaxel and carboplatin alone in treating stage III/IV endometrial  cancer and to find out what side effects are caused by treatment with these drugs.  

  • RTOG 0724
  • The purpose of this study is to compare the effects, good and/or bad, of giving additional chemotherapy to you after the usual treatment of chemotherapy and radiation for your cervical cancer.