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Locate Available Clinical Trials

To view available Clinical Trial information choose from the list on the right or search using the fields below.

 

 

trial #
trial description
  • Alliance A211401
  • The purpose of this study is to see if post-operative complications can be reduced by helping patients stop smoking with a drug called varenicline (also called Chantix®) and using National Cancer Institute Tobacco Quitline for counseling. This study will see how well the drug varenicline helps you stop smoking by comparing it to a placebo. A placebo is a pill that looks like the study drug but contains no medication.

  • Alliance A221602
  • The purpose of this study is to see if Olanzapine given in combination with other drugs, is still as effective without the Fosaprepitant for patients taking chemotherapy. Information from this study will also be used by researchers at the University of Chicago to evaluate health care costs when taking treatments used for nausea and vomiting.

     

  • Alliance/CCTG CE.7
  • This study is being done to answer the following questions:  Can we reduce your symptoms and lower the chance of the cancer growing or getting worse by using stereotactic radiosurgery, compared to the usual radiotherapy?  Stereotactic radiosurgery or SRS is a commonly used treatment for brain tumors.  It is a one-day (or in some cases two day), out-patient procedure during which a high dose of radiation is delivered to small spots in the brain while excluding the surrounding normal brain.We are doing this study because we want to find out if this approach is better or worse than the usual approach for your type of cancer. 

     

  • CTSU E1Q11
  • The purpose of this study is to see if establishing a reproductive health program will help to address the reproductive needs of women in the 18-55 age group who are diagnosed with cancer. This will be done through an intervention. Questionnaires that will be completed regarding your healthcare practice in general as well as specific to patients eligible for this study will serve as important measures.

  • CTSU EAY131
  • DCP-001
  • The purpose of this project is to understand why patients do notparticipate in clinical trials. This information will help researchers design future studies. Also, to address the reasons people do not participate, especially young adults and teenagers, older people and minorities. In addition, personal and medical information will be collected to help understand differences in treatment and treatment outcomes among these populations. The data collected will be used by: 1) NCI to evaluate the overall performance of the community program (NCORP) 2) The medical team to better understand reasons patients don’t participate, especially reasons related to the institution or the clinical trial 3) Researchers to improve the design of current and future studies 4) Researchers to develop research questions such as differences in access to care, treatment received and the outcome of the treatment received by different populations.
  • NRG-CC004
  • Sexual health after treatment for cancer is an important survivorship issue. This study will address the common side effect of decreased sexual health in women who have been treated for breast or gynecologic cancer. The study will test whether bupropion, a medication that is approved for depression and smoking cessation can improve sexual desire compared to placebo. 

  • URCC 13059
  • The purpose of this study is to find out if the Geriatric Assessment can help improve and develop a standard approach for reducing and/or preventing chemotherapy side effects in older cancer patients.  The GA is designed to evaluate an older patient’s overall health and assesses the following areas: nutritional status; social support; physical performance (walking, leg strength, and balance); function, physical ability, and memory.  If you decide to participate in this study, you will receive a Geriatric Assessment (GA). 

  • URCC 16092
  • The purpose of this study is to see if adding either prochlorperazine or olanzapine to the standard antiemetic regimen of Akynzeo and dexamethasone at chemotherapy cycle 2 can improve chemotherapy-related nausea and vomiting in people who experienced it at chemotherapy cycle 1.  We also want to find out if either of these drugs is more effective than the other in controlling chemotherapy-related nausea and vomiting.  In this study you will get the standard antiemetic regimen of Akynzeo and dexamethasone.  Additionally, you will get either prochlorperazine or olanzapine or a placebo.  Prochlorperazine and olanzapine are drugs approved by the Food and Drug Administration to be used for nausea and vomiting.  A placebo is lactose filled capsule made to look exactly like the prochlorperazine and olanzapine capsules, but has no active medication in it. 

     

  • WF 01213
  • The purpose of this research study is to determine our ability to recruit lung cancer survivors who have completed cancer treatment to a study of a device that may decrease anxiety. We then will determine how many will complete the sessions using the study device as well as all study questionnaires. We will also compare effects of device-guided breathing on anxiety and shortness of breath in lung cancer survivors.

     

  • WF 97116
  • Donepezil is currently FDA approved for the treatment of mild to moderate dementia of the Alzheimer’s type, but not for its use in this study evaluating cancer-related cognitive dysfunction in breast cancer survivors.

    The purpose of this study is to compare the safety and effects of donepezil (called Aricept) or placebo on people and their risk of memory problems after receiving chemotherapy for breast cancer.

                      

  • WF 97415
  • The purpose of this study is to compare these effects on women receiving chemotherapy for breast cancer compared to women who are healthy and do not receive chemotherapy.