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Locate Available Clinical Trials

To view available Clinical Trial information choose from the list on the right or search using the fields below.

 

 

trial #
trial description
  • Alliance A011104
  • The purpose of this study is to test whether patients undergoing a breast MRI (called magnetic resonance imaging) before breast cancer surgery will have better results after the surgery.

  • Alliance A211102
  • The purpose of this research study is to test whether metformin, a drug commonly used to treat diabetes, is able to get rid of atypia (or marker of breast cancer risk) in women at increased risk for breast cancer.  We will test for the presence of atypia in the breast after metformin is given to see if it can get rid of atypia. We would like to compare the effects, good and/or bad, of metformin or placebo on atypia to find out which is better.  In this study, you will get either metformin or a placebo (an inactive product) for the first twelve months.  After the first twelve months, women who received placebo during the first twelve months can choose to receive metformin for the second year.

  • Alliance A211201
  • This study is being done as a related study to the MA.32 clinical trial (also called a “companion study”), to see if the use of metformin causes a decrease in mammographic breast density.The breast is composed of fat, milk glands, and various other tissues, which determine how dense the breasts are. High breast density has been shown to be a strong risk factor for developing breast cancer. It is thought that decreasing breast density may decrease the risk for breast cancer. The main goal of this study is to see whether women treated with metformin will have reduced breast density as seen on a mammogram.

  • Alliance A221101
  • The purpose of this study is to see if taking the study drug, armodafinil, at a dose of 150mg or 250mg, will improve problems with fatigue in patients who have been diagnosed with brain cancer and are experiencing fatigue. In this study, you will take either the study drug, armodafinil, or the placebo (inactive drug).  You will not take both. 

  • Alliance A221102
  • The purpose of this study is to compare the effects, good and/or bad, of the study drug, testosterone, with a placebo (an inactive drug) on joint pain caused by taking aromatase inhibitors for treatment of breast cancer.  The testosterone will be mixed with a little anastrozole to prevent any medication from turning into estrogen. The testosterone/placebo is a pellet that is placed just under your skin on the upper buttocks or lower abdomen.  In this study, you will receive either the testosterone or placebo.  You will not receive both. 

  • CTSU EAQ152
  • NRG/GOG 0225
  • The purpose of this study is to find out if a change in diet and exercise in women with primary peritoneal, fallopian tube and ovarian cancer has an effect on the length of time you are cancer free following your initial treatment.

  • NRG/GOG 0237
  • The main purpose of this study is to determine whether the presence of human Papillomavirus (called HPV) and certain chemical substances (called biomarkers) in cervical cells can help identify which women with a cytologic diagnosis of AGC have a benign condition and which have a pre-cancerous condition or an invasive cancer that requires surgical removal.  

  • SWOG S0820
  • The purpose of this study is to determine if eflornithine and sulindac, taken alone or in combination, can decrease the risk of high-risk adenomas or second primary colorectal cancers in patients who have been treated for Stage 0, I, II or III colon cancer. 

  • URCC 14040
  • Sleep disturbance, particularly insomnia, is a common problem for cancer survivors.  Insomnia can be described as excessive daytime napping, difficulty falling asleep, difficulty staying asleep, or waking up earlier than you would like.  Insomnia can increase fatigue, impair physical function, impair immune function, cause circadian rhythms (known as your biological clock) to be disrupted and decrease quality of life. Because there is no ideal standard of care for effectively treating sleep problems in cancer survivors, the purpose of this study is to compare the effectiveness of three different treatments for improving sleep problems and determine which is best.  The three treatments are yoga, survivorship health education, and cognitive behavioral therapy.